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中文名稱：1,4-二氧雜環(huán)-2,5-己二酮、乙交酯、羥基乙酸交酯

英文名稱：1,4-Dioxane-2,5-dione、Glycolide、2,5-dioxo-1,4-dioxane

乙交酯是α羥基酸的環(huán)狀二聚體，可用于制備脂肪族聚酯。它通過(guò)甘醇酸的二聚化而合成。它可制備低毒的人造生物可降解聚合物，適于醫(yī)療應(yīng)用。它主要用于通過(guò)開(kāi)環(huán)聚合反應(yīng)形成高度結(jié)晶的聚乙交酯。

乙交酯作為聚合單體，既可以均聚得到聚乙交酯，又可以和其他環(huán)狀單體開(kāi)環(huán)共聚，得到無(wú)規(guī)共聚物或嵌段共聚物，它們作為可生物降解的高分子材料中的一類，在醫(yī)用高分子材料的研究和開(kāi)發(fā)中占有重要地位，在手術(shù)縫合線、人造皮膚及血管、骨骼固定及修復(fù)、藥物控制釋放、組織工程等許多領(lǐng)域得到了應(yīng)用。

Glycolide is α The cyclic dimer of hydroxyl acid can be used to prepare aliphatic polyester. It is synthesized by the dimerization of glycolic acid. It can prepare artificial biodegradable polymers with low toxicity and is suitable for medical applications. It is mainly used to form highly crystalline polyglycolide through ring opening polymerization.

As a polymeric monomer, glycolide can be homopolymerized to polyglycolide, and can also be ring opened copolymerized with other cyclic monomers to obtain random copolymers or block copolymers. As a kind of biodegradable polymer materials, they play an important role in the research and development of medical polymer materials, and play an important role in surgical suture, artificial skin and blood vessels, bone fixation and repair, drug controlled release Tissue engineering and many other fields have been applied.